Tinctura Sanguinariae (U. S. P.)—Tincture of Sanguinaria.

Related entry: Sanguinaria (U. S. P.)—Sanguinaria

SYNONYMS: Tincture of bloodroot.

Preparation.—"Sanguinaria, in No. 60 powder, one hundred and fifty grammes (150 Gm.) [5 ozs. av., 127 grs.]; acetic acid, twenty cubic centimeters (20 Cc.) [325♏]; alcohol, water, each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix alcohol and water in the proportion of six hundred cubic centimeters (600 Cc.) [20 fl℥, 138♏] of alcohol to four hundred cubic centimeters (400 Cc.) [13 fl℥, 252♏] of water. Moisten the powder with one hundred cubic centimeters (100 Cc.) [3 fl℥, 183♏] of the mixture to which the acetic acid had previously been added, and macerate for 24 hours; then pack it firmly in a cylindrical glass percolator, gradually pour on more of a mixture of alcohol and water, made in the same proportions as before, and continue the percolation, until one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏] of tincture are obtained"—(U. S. P.). The acetic acid in this preparation very materially assists in the extraction of the virtues of the drug, and prevents, in a measure, the precipitation which is liable to occur. This tincture has the characteristic acidity of the drug and is of a deep brown-red color.

Action, Medical Uses, and Dosage.—In the dose of 2 to 4 fluid drachms, this tincture will prove emetic; and from 10 to 60 drops will act as a nauseant, expectorant, stimulant, and alterative (see Sanguinaria.).

Tinctura Sanguinariae Acetata Composita.—Compound Acetated Tincture of Sanguinaria.

SYNONYMS: Compound acetated tincture of bloodroot, Acetous emetic tincture.

Preparation.—Take of bloodroot, lobelia, skunk-cabbage root, each, in fine powder, 2 ounces; distilled vinegar, 2 pints, or a sufficient quantity; alcohol, 2 fluid ounces. Place the drugs in the vinegar, and form into a tincture by maceration or percolation, as explained under Tincturae, and make 2 pints of tincture, to which add the alcohol.

Action, Medical Uses, and Dosage.—This preparation was formerly much used by physicians as an emetic and expectorant, in all cases where such agents were required. As an emetic, the dose is from 1 to 4 fluid drachms, in some sweetened aromatic infusion, to be repeated every 10 or 15 minutes until vomiting is produced; as an expectorant the dose is from 20 to 60 drops, every 1 or 2 hours. It also forms a useful external application to erysipelas, tetter, and other forms of cutaneous disease.

Related Tincture.—TINCTURA SANGUINARIAE COMPOSITA, Compound tincture of bloodroot, Emetic tincture. Take of bloodroot, lobelia, skunk-cabbage root, each, in fine powder, 2 ounces; diluted alcohol, 2 pints, or a sufficient quantity. Form into a tincture by maceration or percolation, as explained under Tincturae, and make 2 pints of tincture. This tincture is used for the same purposes, in the same manner and dose, as the preceding.

King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.