Tinctura Colchici Composita.—Compound Tincture of Colchicum.
Related entry: Colchicum.—Colchicum
Preparation.—Take of colchicum seed, in fine powder, 2 ounces; black cohosh root, in fine powder, 3 ounces; diluted alcohol, 2 pints, or a sufficient quantity. Form it into a tincture by maceration or percolation, and make 2 pints of tincture. Or, it may be made by adding together equal parts of the tinctures of colchicum seed and black cohosh root.
Action, Medical Uses, and Dosage.—This forms an excellent agent in inflammatory rheumatism and gout, and has proved a superior remedy in phlegmasia dolens, or the swelled leg of parturient women. The dose is from 10 to 60 drops, or more, as circumstances indicate, every 1, 2, 3, or 4 hours. Iodide of potassium, 15 grains to 1 ounce of the tincture, may frequently be added with advantage (J. King).
Tinctura Colchici Seminis (U. S. P.)—Tincture of Colchicum Seed.
(Modern shorthand: 1:6.7 60 %)
SYNONYMS: Tincture of colchicum, Tinctura colchici (U. S. P. 1880).
Preparation.—"Colchicum seed, in No. 30 powder, one hundred and fifty grammes (150 Gm.) [5 ozs. av., 127 grs.]; alcohol, water, each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix alcohol and water in the proportion of six hundred cubic centimeters (600 Cc.) [20 fl℥, 138♏] of alcohol and four hundred cubic centimeters (400 Cc.) [13 fl℥, 252♏] of water. Having moistened the powder with one hundred cubic centimeters (100 Cc.) 13 fl℥, 183♏] of the menstruum, macerate for 24 hours; then pack it moderately in a cylindrical percolator, and gradually pour menstruum upon it, until one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏] of tincture are obtained"—(U. S. P.). This produces a bitter, brown-yellow tincture, striking opalescent with water.
Action, Medical Uses, and Dosage.—This tincture may be used wherever colchicum is indicated. It is also employed as an external application in gouty, neuralgic, and rheumatic pains. The dose is from 30 drops, cautiously increased to 1 or 2 fluid drachms.
King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.
