Fldext. Casc. Sagr. Arom. [Fluidextractum Rhamni Purshianae Aromaticum. U. S. VIII]
Related entries: Cascara Sagrada
Tasteless Fluidextract of Cascara Sagrada; Extrait liquid Aromatique de Cascara Sagrada, Fr.; Bitterloses flüssiges Cascara-Sagradaextrakt, G.
"Cascara Sagrada, in No. 40 powder, one thousand grammes [or 35 ounces av., 120 grains]; Magnesium Oxide, one hundred and twenty-five grammes [or 4 ounces av., 179 grains]; Pure Extract of Glycyrrhiza, forty grammes [or 1 ounce av., 180 grains]; Glycerin, two hundred mils [or 6 fluidounces, 366 minims]; Alcohol, two hundred and fifty mils [or 8 fluidounces, 218 minims]; Benzosulphinide, one gramme [or 15 grains]; Oil of Anise, two and five-tenths mils [or 40 minims]; Oil of Cinnamon, two-tenths of a mil [or 3 minims]; Oil of Coriander, one-tenth of a mil [or 1 1/2 minims]; Methyl Salicylate, two-tenths of a mil [or 3 minims]; Boiling Water, a sufficient quantity, to make one thousand mils [or 33 fluid-ounces, 6 1/2 fluidrachms]. Thoroughly mix the cascara sagrada "with the magnesium oxide, moisten the mixture with two thousand mils [or 67 fluidounces, 301 minims] of boiling water, set it aside for two hours, stirring occasionally, and then pack it in a percolator. Now pour on boiling water and allow the percolation to proceed until the drug is exhausted. Evaporate the percolate to five hundred mils [or 16 fluid-ounces, 435 minims] and while yet warm dissolve in it the extract of glycyrrhiza. When cold, add the glycerin, then the alcohol in which the benzosulphinide and the oils have been dissolved, and finally sufficient water to make the Fluidextract measure one thousand mils [or 33 fluidounces, 6 1/2 fluidrachms]." U. S.
An aromatic fluidextract was introduced into the U. S. P. VIII for the first time. It is given as a laxative, the object of the addition of magnesium oxide is to destroy the bitter taste of the cascara sagrada. Lime is sometimes used instead of magnesia but it has been shown that lime acts injuriously upon the laxative principles of cascara sagrada.
Dose, fifteen minims to one fluidrachm (0.9-3.75 mils).
Off. Prep.—Elixir Cascarae Sagradae, N. F.; Elixir Cascarae Sagradae Compositum, N. F.
The Dispensatory of the United States of America, 1918, was edited by Joseph P. Remington, Horatio C. Wood and others.