Manzanillo. Manchineel. Hippomane Mancinella L.—According to A. Betancourt, the milky juice of this euphorbiaceous tree, growing in the West Indies, is a violent irritant, acting as a vesicant when applied to the skin, and when taken internally in doses of twenty drops causing a fatal gastro-enteritis. In doses of two drops it acts as a powerful and very certain cathartic; it is also diuretic. In Cuba it has much repute in tetanus. (L.M.R., Feb., 1889.)
The Dispensatory of the United States of America, 1918, was edited by Joseph P. Remington, Horatio C. Wood and others.