Tinctura Aurantii, Br.; Tincture of Orange; Teinture (alcoole) d'Ecorce d'Orange amere, Fr.; Tinctura Aurantii, P. G,; Pomeranzentinktur, Pomeranzenschalentinktur, G.
*Bitter Orange Peel, in No. 40 powder, two hundred grammes [or 7 ounces av., 24 grains], to make one thousand mils [or 33 fluid-ounces, 6 1/2 fluidrachms]. Prepare a Tincture by Type Process P, using a mixture of three volumes of alcohol and two volumes of water as the menstruum." U. S.
"Fresh Bitter-Orange Peel, cut small, 250 grammes; Alcohol (90 per cent.), 1000 millilitres. Prepare by the maceration process." Br.
It is the peel of the Seville orange that is directed in this process, and the outer part only is active. The substitution of fresh for dried orange peel was proposed in England, and its propriety considerably discussed. (See P. J., Nov. 9, 1872, also April 4, 1874.) Indeed, it met with so much favor as to be introduced in the 1885 revision of the British Pharmacopoeia, and was used in the Tinctura Aurantii Recentis, Br.; but in the Br. Pharm., 1898, the name was changed to Tinctura Aurantii. The two tinctures differ also because of the fact that the Br. "orange peel" is only of the outer layer, while the U. S. includes also the inner, white, portion of the rind. The U. S. tincture has a greenish-brown color and a bitterish taste, the latter due to the presence of hesperidin from the inner layer of the rind. The Br. tincture of orange more closely resembles the U. S. Tinctura Aurantii Dulcis in sensible properties. The tincture of bitter orange peel is employed as a grateful addition to infusions, decoctions, and mixtures.
Dose, from one to two fluidrachms (3.75-7.5 mils).
The Dispensatory of the United States of America, 1918, was edited by Joseph P. Remington, Horatio C. Wood and others.