Related entries: Rubus (U. S. P.)—Rubus
SYNONYM: Fluid extract of blackberry bark.
Preparation.—"Rubus, in No. 60 powder, one thousand grammes (1000 Gm.) [2 lbs. av., 3 ozs., 120 grs.]; glycerin, one hundred cubic centimeters (100 Cc.) [3 fl℥, 183♏]; alcohol, water, each, a sufficient quantity to make one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]. Mix the glycerin with six hundred cubic centimeters (600 Cc.) [20 fl℥, 138♏] of alcohol and three hundred cubic centimeters (300 Cc.) [10 fl℥, 69♏] of water, and, having moistened the powder with three hundred and fifty cubic centimeters (350 Cc.) [11 fl℥, 401♏] of the mixture, pack it firmly in a cylindrical percolator; then add enough menstruum to saturate the powder and leave a stratum above it. When the liquid begins to drop from the percolator, close the lower orifice, and, having closely covered the percolator, macerate for 48 hours. Then allow the percolation to proceed, gradually adding, first, the remainder of the menstruum, and afterward a mixture of alcohol and water, made in the proportion of six hundred cubic centimeters (600 Cc.) [20 fl℥, 138♏] of alcohol and three hundred cubic centimeters (300 Cc.) [10 fl℥, 69♏] of water, until the rubus is exhausted. Reserve the first seven hundred cubic centimeters (700 Cc.) [23 fl℥, 321♏] of the percolate. Distill off the alcohol from the remainder by means of a water-bath, and evaporate the residue to a soft extract; dissolve this in the reserved portion, and add enough of the mixture of alcohol and water, using the last-named proportions, to make the fluid extract measure one thousand cubic centimeters (1000 Cc.) [33 fl℥, 391♏]"—(U. S. P.).
Description, Medical Uses, and Dosage.—A strongly astringent, dark red-brown, translucent liquid. Dose, 30 minims to 2 fluid drachms.
King's American Dispensatory, 1898, was written by Harvey Wickes Felter, M.D., and John Uri Lloyd, Phr. M., Ph. D.